目的:研究T淋巴细胞亚群与带状疱疹后遗神经痛发病的关系。方法:测定接受不同治疗方案的两组患者治疗前后外周血T淋巴细胞亚群值并进行比较。结果:50例带状疱疹患者经转移因子治疗后CD3、CD4、CD4CD8明显高于治疗前,且带状疱疹后遗神经痛发病率显著降低;21例带状疱疹后遗神经痛患者CD3、CD4、CD4CD8均明显低于对照组。结论:带状疱疹后遗神经痛患者T淋巴细胞亚群免疫功能低下,加用转移因子能有效预防带状疱疹后遗神经痛的发生。 Objective: To study the relationship between T lymphocyte subsets and postherpetic neuralgia. Methods: Peripheral blood T lymphocyte subsets were measured and compared before and after treatment in two groups receiving different treatment regimens. Results: The incidence of postherpetic neuralgia was significantly lower in 50 cases of shingles treated with transfer factor than those before treatment, and 21 cases of postherpetic neuralgia CD3, CD4, CD4 CD8 were significantly lower than the control group. Conclusion: The immune function of T lymphocyte subsets in patients with postherpetic neuralgia is poor. Addition of transfer factor can effectively prevent the occurrence of postherpetic neuralgia.