目的 :探讨糖尿病患者血脂、载脂蛋白变化及其诱发心血管并发症的致病因素。方法 :采用酶法及免疫透射比浊法 ,分别测定糖尿病患者及健康人的空腹血糖 (FPG)、总胆固醇 (CH)、甘油三酯 (TG)、高密度脂蛋白 (HDL)、低密度脂蛋白 (L DL)、载脂蛋白 A1(Aop A1)及载脂蛋白 B(Apo B)水平 ,并进行组间比较分析。结果 :糖尿病患者 FBG、CH、TG、L DL 及 Apo B水平与健康对照组比较具有显著性意义 (P<0 .0 1)。结论 :糖尿病患者血脂、载脂蛋白的改变是预测糖尿病诱发动脉粥样硬化、冠心病的重要指标。 Objective: To investigate the changes of blood lipids, apolipoproteins and the risk factors of cardiovascular complications in diabetic patients. Methods: The levels of fasting blood glucose (FPG), total cholesterol (CH), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein L DL, Aop A1 and Apo B were measured and compared between groups. Results: The levels of FBG, CH, TG, L DL and Apo B in diabetic patients were significantly higher than those in healthy controls (P <0.01). Conclusion: The changes of blood lipids and apolipoproteins in diabetic patients are important indexes for predicting diabetes-induced atherosclerosis and coronary heart disease.