人麻风病的病源微生物——麻风杆菌迄今未成功地被培养,几乎我们所有关于这种微生物的知识都来自1960年Shepard氏首先描述的鼠足垫感染。但是,由于麻风分枝杆菌在鼠足垫中仅属有限增殖,且缺乏引起与人的瘤型麻风病相似的损害,故作为播散性麻风病的模型已受到限制。 1971—1972年,Kirchheimer和Storrs二氏报道了用人麻风分枝杆菌实验感染未受人 To date, none of the leprosy-producing microbes, Leprosy, has been successfully cultivated. Almost all of our knowledge of this microorganism comes from the first mouse footpad infection described by Shepard in 1960. However, as a model of disseminated leprosy, the restriction of M. leprae is limited due to the limited proliferation of M. leprae in mouse foot pads and its lack of similar damage to human neoplastic leprosy. From 1971 to 1972, Kirchheimer and Storrs II reported that people infected with M. lepra were not infected with human