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目的分析2型糖尿病合并骨质疏松症的相关因素,以期对相关危险因素进行有针对性的预防。方法选择2015年1月-12月在该院就诊并确诊的2型糖尿病并发骨质疏松症患者50例作为试验组,以同时期在该院就诊并确诊的正常骨密度的2型糖尿病患者50例作为对照组,测量患者的骨密度值及促黄体生成素(LH)、雌二醇(E2)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、糖化血红蛋白(Hb A1c)、促卵泡生成激素(FSH)、三酰甘油(TG)、空腹胰岛素(FINS)等生化指标。结果试验组女性比例明显多于男性,与对照组比较差异有统计学意义(χ2=6.760,P<0.05)。患者性别、年龄、病程、Hb A1c、FSH、LH、BMI、E2与骨质疏松症有明显相关性(P<0.05),FBG、TG、LDL-C、FINS与骨质疏松症无明显相关性(P>0.05)。结论 2型糖尿病患者并发骨质疏松症有明显的危险因素,应针对危险因素提前做好干预,预防患者骨质疏松症的发生。
Objective To analyze the related factors of type 2 diabetes mellitus with osteoporosis in order to prevent the related risk factors. Methods Fifty patients with type 2 diabetes mellitus and osteoporosis admitted to our hospital from January to December in 2015 were selected as the experimental group and 50 normal type 2 diabetics with normal bone density As control group, the bone mineral density (BMD) and the serum levels of LH, E2, LDL-C, FBG, Hb A1c were measured. , Follicle stimulating hormone (FSH), triglyceride (TG), fasting insulin (FINS) and other biochemical indicators. Results The proportion of women in experimental group was significantly higher than that in male group (χ2 = 6.760, P <0.05). The gender, age, course of disease, HbA1c, FSH, LH, BMI and E2 had significant correlation with osteoporosis (P <0.05). There was no significant correlation between FBG, TG, LDL-C and FINS and osteoporosis (P> 0.05). Conclusion Patients with type 2 diabetes complicated with osteoporosis have obvious risk factors. Interventions should be made according to risk factors in advance to prevent the occurrence of osteoporosis in patients.