凋亡对组织发育、维持内环境稳定有着极其重要的作用。细胞过度增殖或死亡减少会导致自身免疫性疾病或肿瘤形成。对小线虫(Celegans)凋亡调节基因的研究证实凋亡由遗传基因控制,基因突变引起凋亡抑制。哺乳动物内存在内源性线粒体通路和外源性死亡受体通路。线粒体死亡通路有bc Apoptosis plays an extremely important role in the development of tissues and maintaining the stability of the internal environment. Decreased cell proliferation or death leads to autoimmune diseases or tumor formation. Studies on the genes regulating the apoptosis of Celegans confirm that apoptosis is controlled by genes and that mutations cause apoptosis inhibition. Mammalian memory exists in endogenous mitochondrial and extrinsic death receptor pathways. Mitochondrial death pathway with bc