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目的 探讨重症严重急性呼吸道综合征 (SARS)预后相关的因素。方法 以山西省 2 0 0 3年 3月7日至 6月 4日临床诊断重症 SARS 10 2例患者为研究对象 ,通过回顾性分析 ,比较存活病例与死亡病例流行病学资料、临床资料、实验室检查及临床治疗措施 ,并对死亡相关因素作单因素及多因素 L ogistic回归分析。结果 1年龄、基础疾病、直接接触史 ,发病早期末梢血淋巴细胞百分比、心理治疗是重症 SARS预后预测因素。2年龄 ,心理治疗及发病早期末梢血淋巴细胞数与患者死亡显著相关 ,是重症 SARS预后独立影响因素。结论 1年龄 >5 0岁 ,早期末梢血淋巴细胞百分比低于正常提示重症 SARS病例预后不良 ;2联合使用药物治疗和心理治疗 ,可改善重症 SARS病例预后 ,促进康复
Objective To explore the prognostic factors of severe acute respiratory syndrome (SARS). Methods A total of 102 patients with severe SARS diagnosed in Shanxi Province from March 7 to June 4, 2003 were enrolled in this study. By means of retrospective analysis, the epidemiological data, clinical data and experiment of survivors and deaths were compared Room examination and clinical treatment measures, and univariate and multi-factor L ogistic regression analysis of death-related factors. Results 1 Age, underlying disease, history of direct exposure, percentage of peripheral blood lymphocytes in early onset, and psychotherapy were predictors of severe SARS outcomes. 2 age, psychological treatment and the early onset of peripheral blood lymphocytes and the number of deaths were significantly correlated with the independent prognosis of severe SARS independent factors. Conclusion 1 The age of> 50 years old, the percentage of early peripheral blood lymphocytes is lower than that of normal prompt severe SARS patients with poor prognosis; 2 combination of drug treatment and psychological treatment can improve the prognosis of severe SARS cases and promote rehabilitation