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β -环糊精 (简称β—ＣＤ〉是一种有效的药用赋形剂 ,在药学领域应用很广泛 ,但它的水溶性很小 ,其包合物胃肠外给药后可在肾中产生结晶而导致毒性。而且 β -ＣＤ的羟基呈现类似酶催化作用 ,影响了药物的稳定性。为了克服这些缺点 ,需要对其进行结构改造。目前对改性 β -Ｃ
β - Cyclodextrin (β - CD) is an effective pharmaceutical excipient which is widely used in the field of pharmacy. However, its solubility in water is very small. Its inclusion compound can be administered in the kidney after parenteral administration In the resulting crystallization and lead to toxicity.And β -CD hydroxyl showed similar enzyme catalysis, affecting the stability of the drug.In order to overcome these shortcomings, the need for its structural transformation.Current modified β-C