论文部分内容阅读
观察了322例癫痫患者血清免疫球蛋白、补体C_3和循环免疫复合物(CIC)含量与脑电图波形的关系。结果发现,脑电图出现癫痫波形者较未出现癫痫波形者或对照组,其IgA平均含量显著降低(P<0.01),CIC平均含量显著增高(P<0.01),IgM平均含量轻度升高,这些变化与患者是否服用抗痫药物、发作类型及年龄等因素似无关系。其它所测免疫指标与脑电图不同波形之间比较无明显差异。提示癫痫放电波可能是造成癫痫患者某些免疫指标异常的重要原因之一。
The relationship between serum immunoglobulin, complement C_3 and circulating immune complex (CIC) levels and EEG waveforms in 322 epileptic patients was observed. The results showed that the average IgA content was significantly lower (P <0.01), the average content of CIC was significantly higher (P <0.01), and the average IgM content was slightly higher in EEG epileptic patients than those without epileptic symptoms , These changes and whether the patient taking anti-epileptic drugs, seizure types and age factors seem to be unrelated. Other measured immune parameters and EEG different waveforms between the no significant difference. It is suggested that epileptic discharge wave may be one of the important causes of some abnormal immune parameters in patients with epilepsy.