论文部分内容阅读
1981年在Oslo召开的第六届人类基因定位国际会议中成立了一个专门小组,以期能提供一份非随机的与特异肿瘤恶性增殖有关的专一断裂点的目录.1983年在LosAngeles举行的第七届人类基因定位国际会议成立了一个委员会并决定发表关于脆性部位的报告.把肿瘤形成中的染色体重排作为一个独立委员会报告,其理由是某些染色体重排的类型(例如特异的易位)导致在正常情况下相距较近的DNA顺序的物理近似值.这些染色体重排的结果,可能是产生新的异常DNA顺序的产物,这已由最近对慢性粒细胞白血病的分子生物学的研究所证实.
A special group was established at the 6th International Conference on Human Genotyping in Oslo in 1981 to provide a non-random list of specific breakpoints associated with malignant proliferation of specific tumors. The first in 1983 was held in Los Angeles. A seven-nation human gene mapping international conference established a committee and decided to publish a report on fragile parts. The chromosomal rearrangement in tumor formation was reported as an independent committee on the grounds that certain types of chromosome rearrangements (such as specific translocations) ) Physical approximations that result in DNA sequences that are closer together under normal conditions. The result of these chromosome rearrangements may be the product of new abnormal DNA sequences, which has been recently studied by the Institute of Molecular Biology of Chronic Myeloid Leukemia Confirmed.