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成纤维细胞生长因子受体是一类具有自身磷酸化活性的 型跨膜糖基化受体 ,其家族成员都是酪氨酸激酶受体 ,在细胞的增殖、分化、血管生成、骨骼形成、伤口愈合和生长发育等进程中起着十分重要的作用。作者综述了 FGFR3的结构和功能特点以及 FGFR3与疾病的关系
Fibroblast growth factor receptor is a type of transmembrane glycosylation receptor with autophosphorylation activity, its family members are tyrosine kinase receptors, in cell proliferation, differentiation, angiogenesis, bone formation, Wound healing and growth and development process plays a very important role. The authors reviewed the structural and functional characteristics of FGFR3 and the relationship between FGFR3 and disease