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目的:观察放化疗配合中医辨证治疗脑转移瘤临床疗效。方法:67例患者随机分为化疗配合中药组(观察Ⅰ),放疗配合中药组(观察Ⅱ)与单纯化疗组(对照Ⅰ),单纯放疗组(对照Ⅱ),对4组疗效作比较观察。结果:观察Ⅰ、Ⅱ组患者近期有效率(完全缓解加部分缓解)、生存质量、1~4年生存率及中位生存时间、部分免疫功能指标明显高于对照Ⅰ、Ⅱ组(P<005)。结论:放化疗配合中医辨证治疗脑转移瘤,具有抑制肿瘤生长,延长生存时间,提高生存质量之效。
Objective: To observe the clinical efficacy of radiotherapy and chemotherapy combined with traditional Chinese medicine in treating brain metastases. Methods: Sixty-seven patients were randomly divided into chemotherapy combined with traditional Chinese medicine group (observation Ⅰ), radiotherapy combined with traditional Chinese medicine group (observation Ⅱ) and chemotherapy alone group (control Ⅰ) and radiotherapy alone group (control Ⅱ). Results: The effective rate (complete remission plus partial remission), quality of life, 1 to 4 years survival rate and median survival time were observed in group Ⅰ and group Ⅱ, and some immune function indexes were significantly higher than those in group Ⅰ and Ⅱ (P <0 05). Conclusion: Radiotherapy and chemotherapy combined with TCM treatment of brain metastases have the effect of inhibiting tumor growth, prolonging survival and improving quality of life.