观察了20例EHF患者的自发性抑制性T细胞(ST_s)功能,发现在病之极期ST_s活性显著低于正常(-49.07％vs.22.51％,P<0.001),多尿期和恢复期逐渐回升并趋向正常。轻症组患者极期的ST_s活性较重症组下降更为明显(-85.42％vs,-12.7％,P<0.05)。初步认为T_s功能低下是EHF体液免疫亢进的基本原因。T_s功能下降,使T_h和T_c功能相对增强,有利于清除病毒,终止感染,这可能是机体的一种保护性免疫反应。本文还提出关于EHF免疫调节过程的假设。 The spontaneous inhibitory T-cell (ST_s) function was observed in 20 patients with EHF and found that the ST_s activity was significantly lower than the normal (-49.07% vs.22.51%, P <0.001), polyuria and convalescent Gradually picked up and tends to normal. In the mild group, the peak of ST_s activity was more significant in the severe group (-85.42% vs -12.7%, P <0.05). It is initially believed that T_s dysfunction is the basic cause of EHF humoral immunity. T_s function decline, T_h and T_c function is relatively enhanced, help clear the virus, termination of infection, which may be the body’s protective immune response. This article also presents assumptions about the immune regulation of EHF.