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目的 :了解泮托拉唑治疗十二指肠溃疡的疗效和安全性。方法 :82例十二指肠溃疡患者随机分为 2组 ,各 41例。分别服泮托拉唑 40mg和奥美拉唑 2 0mg ,qd ,疗效均为 2周。 结果 :两组溃疡愈合率分别为 75 6 %和 6 8 3% ,总有效率分别为 97 6 %与 10 0 % ,两组间无显著性差异 (P >0 0 5 ) ;两组腹痛消失时间分别为 (3 1±1 5 )和 (3 2± 1 6 )d ,无显著差别 (P >0 0 5 )。结论 :2周常规剂量 ,泮托拉唑可有效地愈合溃疡和缓解症状
Objective: To understand the efficacy and safety of pantoprazole in the treatment of duodenal ulcer. Methods: 82 cases of duodenal ulcer patients were randomly divided into two groups, 41 cases each. Pantoprazole 40mg and omeprazole 20mg, qd, respectively, for 2 weeks. Results: The healing rates of ulcer in both groups were 75.6% and 68.3%, respectively. The total effective rates were 97.6% and 100% respectively. There was no significant difference between the two groups (P> 0.05). The abdominal pain disappeared in both groups The time was (3 1 ± 1 5) and (3 2 ± 1 6) d, respectively, with no significant difference (P> 0.05). CONCLUSION: With 2-week conventional dose, pantoprazole can effectively heal ulcers and relieve symptoms