本文介绍了抗生素后效应的定义,可靠机理、作用以及近年来国际医药界对它新的研究进展,为我们的临床合理用药增加了一个新的必需考虑的因素。从而使得我们在设计感染性疾病治疗方案时更加合理、安全、有效。近十年来,抗生素的后效作用(postantibiotic effect PAE)正重新引起人们的重视。 This article introduces the definition of post-antibiotic effect, reliable mechanism and effect as well as the new research progress made by the international medical community in recent years, which adds a new factor that must be considered for our clinical rational drug use. This makes us more rational, safe and effective in the design of infectious disease treatment programs. In the past decade, the postantibiotic effect (PAE) of antibiotics is re-attracting people’s attention.