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目的:分析肺表面活性物质(PS)用于新生儿呼吸窘迫综合征(NRDS),对改善临床症状的效果。方法:选取龙门县人民医院2015年10月至2016年10月收治的NRDS90例作为观察组,将同期该疾病患儿86例作为参照组。参照组患者进行常规治疗;而观察组在此基础上结合PS开展治疗。比较两组患者氧合指数,并对血气分析和呼吸机参数变化和病情转归进行分析。结果:观察组经用药治疗后,患儿呼吸窘迫、皮肤发绀症状、血气分析等临床指标明显得到改善,且呼吸机指数较用药前降低,机械通气时间明显缩短,差异具有统计学意义(P<0.05)。结论:PS对改善新生儿呼吸窘迫综合征临床症状具有积极作用。
Objective: To analyze the effect of pulmonary surfactant (PS) on neonatal respiratory distress syndrome (NRDS) to improve clinical symptoms. Methods: 90 patients with NRDS admitted from Longmen County People’s Hospital from October 2015 to October 2016 were selected as the observation group, and 86 children with this disease were selected as the reference group. The reference group of patients for conventional treatment; while the observation group on the basis of PS with treatment. Oxygenation index was compared between the two groups, and blood gas analysis and changes in ventilator parameters and prognosis were analyzed. Results: After treatment, the clinical indexes such as respiratory distress, cyanosis and blood gas analysis in the observation group were significantly improved, and the index of ventilator was lower than before treatment and the time of mechanical ventilation was significantly shortened (P < 0.05). Conclusion: PS has a positive effect on improving the clinical symptoms of neonatal respiratory distress syndrome.