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目的:探讨狼疮性肾炎(LN)对妊娠结果的影响和妊娠对肾损害过程的影响两者的相互关系。方法:对30例LN病人50次妊娠进行回顾分析。结果:婴儿出生率以LN在缓解期为高,胎儿损耗率在LN活动期妊娠为高,妊娠过程在一定程度上会加重LN,妊娠过程中及产后给予大剂量激素治疗可减少因妊娠导致的LN复发。
Objective: To investigate the effect of lupus nephritis (LN) on the outcome of pregnancy and the influence of pregnancy on the process of renal damage. Methods: A retrospective analysis of 50 pregnancies in 30 patients with LN was performed. Results: The birth rate of LN was high in remission, the rate of fetal loss was high in LN active stage, and the pregnancy process would aggravate LN to a certain extent. Large dose of hormone treatment during pregnancy and postpartum can reduce LN relapse.