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目的:探讨小儿轮状病毒性(RV)腹泻与血清转氨酶异常和心肌酶谱异常的关系。方法:对230例腹泻患儿用胶体金法检测大便RV抗原,并做肝功及心肌酶谱的测定。结果:观察组(大便RV抗原阳性组)与对照组(大便RV抗原阴性组)的血清转氨酶异常与心肌酶谱异常的发生率差异有显著性(P<0.05),转氨酶异常程度与腹泻程度无关;血清心肌酶谱异常程度与脱水程度有关;转氨酶异常发生率与患儿年龄有关,年龄越小越易发生转氨酶异常,血清心肌酶谱异常与年龄无关。结论:RV腹泻可伴有肠道外感染,可引起血清心肌酶谱和转氨酶异常。早期监测心肌酶及肝酶的变化以便临床及早对RV性腹泻患儿进行干预治疗。
Objective: To investigate the relationship between pediatric rotavirus (RV) diarrhea and abnormal serum aminotransferase and myocardial enzymes. Methods: 230 cases of diarrhea in children with colloidal gold method stool RV antigen, and liver function and myocardial enzymes were measured. Results: There was a significant difference in the incidence of abnormal aminotransferase and myocardial enzyme between the observation group (stool RV antigen positive group) and the control group (stool RV antigen negative group) (P <0.05), and the degree of abnormal aminotransferase was not related to the degree of diarrhea ; The level of serum myocardial enzyme abnormality was related to the degree of dehydration; the incidence of abnormal aminotransferase was related to children’s age. The younger the more prone to transaminase abnormalities, the abnormality of serum myocardial enzymes was not related to age. Conclusion: RV diarrhea may be associated with extraintestinal infections that may cause abnormal serum myocardial enzymes and transaminases. Early detection of changes in myocardial enzymes and liver enzymes in order to clinically early intervention in children with RV diarrhea treatment.