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感染了前基因突变株乙型肝炎病毒（HBV）所致的病毒性肝炎被称为“异型”乙型肝炎，其特点是血清中e抗原（HBeAg）阴性而e抗体（抗HBe）阳性[1]。此型肝炎（简称抗HBe阳性肝炎）因其临床表现显著不同于经典乙型肝炎而在近2～3年已引起各国学者的普遍关注。已证实HBV前C基因突变
Viral hepatitis, which is caused by a hepatitis B virus (HBV) infection of a pre-gene mutant strain, is called “atypical” hepatitis B and is characterized by a positive serum e antigen (HBeAg) and a positive anti-HBe ]. This type of hepatitis (referred to as anti-HBe-positive hepatitis) has drawn the universal attention of scholars from various countries in the recent 2-3 years because of its clinical manifestations significantly different from the classical hepatitis B. It has been confirmed that HBV pre-C gene mutation