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青春期多囊卵巢综合征(PCOS)多起病于青春期,发病机制复杂,临床表现多样,这与青春期月经初潮因性腺轴不成熟而导致的无排卵的生理变化表现相似,容易发生漏诊,影响了患PCOS的少女的生活质量,故青春期PCOS的早期诊断和及时治疗极为重要。近年来,随着各种研究手段尤其是高通量测序技术的发展,PCOS的研究有了新进展。该文就青春期PCOS的发病原因、病理生理、诊断、治疗方案的新进展进行综述。
Adolescent polycystic ovary syndrome (PCOS) more than onset in adolescence, the pathogenesis of complex clinical manifestations, which adolescent menarche because of gonadal axis immature physiological changes caused by anovulation similar to the performance of missed diagnosis, affecting the The quality of life of girls suffering from PCOS, so the early diagnosis and timely treatment of puberty PCOS is extremely important. In recent years, with the development of various research methods, especially high-throughput sequencing technologies, new advances have been made in the study of PCOS. This article reviews the pathogenesis, pathophysiology, diagnosis and treatment of adolescent PCOS.