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偏头痛的病因及发病机理十分复杂,近年来研究发现体内镁水平降低在偏头痛的发病中起重要作用。本文根据1962年美国NIH Ad Hoc委员会制定的头痛分类标准,收集偏头痛24例,其中典型偏头痛7例,普通偏头痛17例;男性10例,女性14例;年龄11～51岁(平均32.1岁);病史为1～12年;有家族史者9例。和年龄配比的健康成人男性8例,女性9例为对照组。应用Spectru-Spom-V三极直流等离子体原子发射光电直读光谱仪(DCP-AES)检测病人和对照组血清镁浓度(mmol/L)。结果发现,偏头痛间歇期(19例)血镁浓度为1.08±0.79,发作期(24例)为0.88±0.51,均低于健康对照组1.34±0.53,P分别<0.05,0.01。
The etiology and pathogenesis of migraine is very complicated. In recent years, studies have found that the decrease of magnesium in the body plays an important role in the pathogenesis of migraine. According to the headache classification standard set by the NIH Ad Hoc Committee in 1962, 24 cases of migraine were collected, including 7 cases of typical migraine and 17 cases of common migraine. There were 10 males and 14 females, ranging in age from 11 to 51 years (average 32.1 Years old); history is 1 to 12 years; 9 cases have a family history. Eight healthy adults were matched with age, and nine were women as control group. Serum magnesium concentration (mmol / L) was measured in patients and control groups using the Spectru-Spom-V three-pole DC plasma atomic emission spectrophotometer (DCP-AES). The results showed that the blood magnesium concentration was 1.08 ± 0.79 in intermittent migraine (19 cases) and 0.88 ± 0.51 in episode (24 cases), all of which were lower than that of healthy control group (1.34 ± 0.53, P <0.05, 0.01 respectively).