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急性原发性甲状旁腺亢进症(HPT)是罕见病,但有几组报告病死亡率很高.巴黎圣路易医院自1960至1986年收治原发性HPT1,000例,其中59例为急性HPT,均经手术治疗.急性HPT的诊断标准为:手术证实为原发性HPT,血清钙水平≥3.75mmol/l(150mg/l),具备一项以上严重临床体征者.入院时40%病例属危重患者.59例中男性14例,女性45例,年龄27～87岁,平均58岁.36例(61%)只因急性发作住院才发现原发性HPT,5例在住院前已诊断此症.21例(36%)有原发性HPT的典型病史而住院前未被诊断.临床体征的出现率说明HPT的轻重程度差异很大.全部病例均至少有三项严重体征,最常见的表现为严重衰弱(88%)、神
Acute primary hyperparathyroidism (HPT) is a rare disease, but several groups report a high mortality rate St. Louis Hospital in Paris from 1960 to 1986 were treated with primary HPT 1,000 cases, of which 59 were acute HPT were surgically treated.The diagnostic criteria of acute HPT were: primary HPT confirmed by operation, serum calcium level≥3.75mmol / l (150mg / l), with one or more serious clinical signs.40% Of the 59 patients, 14 were males and 45 were females, ranging in age from 27 to 87 years, with an average of 58. Thirty-six patients (61%) had primary HPT only because of acute exacerbation and 5 were diagnosed before hospitalization 21 cases (36%) had a typical history of primary HPT without being diagnosed before hospitalization, and the incidence of clinical signs showed that the severity of HPT varied widely with at least three severe signs in all cases, the most common Seriously weaker (88%), God