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目的:分析连花清瘟颗粒对小儿肺炎支原体肺炎细胞免疫功能的影响。方法:选取124例肺炎支原体肺炎患儿的临床资料,根据给药方式不同,分为研究组与对照组各62例,对照组予以常规西药治疗,在此基础上研究组予以连花清瘟颗粒治疗,比较两组患儿细胞免疫功能、临床疗效指标以及治疗前后血清炎性因子水平、CRP变化情况。结果:研究组患儿细胞免疫功能指标均优于对照组(P<0.05);研究组患儿肺啰音消失、止咳等所用时间短于对照组(P<0.05);治疗后研究组患儿血清炎性因子水平与CRP浓度均低于对照组(P<0.05)。结论:肺炎支原体肺炎患儿行阿奇霉素联合莲花清瘟颗粒治疗可提高免疫功能,降低炎性因子水平,并缩短止咳、退热等所用时间,值得临床推广应用。
Objective: To analyze the effect of Lianhua Qingwen Granule on immune function of children with Mycoplasma pneumoniae pneumonia. Methods: The clinical data of 124 children with Mycoplasma pneumoniae pneumonia were selected. According to the different administration modes, 62 cases were divided into study group and control group, while the control group were given conventional western medicine. On the basis of this, the study group was given Lianhua Qingwen granules The cellular immune function, clinical curative effect index and the levels of serum inflammatory cytokines and CRP before and after treatment were compared between the two groups. Results: The indexes of cellular immune function in the study group were better than those in the control group (P <0.05). The study time was shorter in the study group than in the control group (P <0.05) Serum inflammatory cytokines and CRP concentrations were lower than the control group (P <0.05). Conclusion: The treatment of mycoplasma pneumonia in children with azithromycin combined with lotus powder can improve immune function, reduce the level of inflammatory cytokines, and shorten the cough, fever and other time spent, worthy of clinical application.