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584例轻型缺血性卒中(MIS)或(TIA)病人随机分为阿斯匹林(ASA)组301例与对照组283例,随访12～60(平均30.2)月的结果发现:ASA组卒中与死亡率(14.0％)明显低于对照组(20.5％)(P<0.05),ASA组卒中与死亡危险性较对照组降低32％(相对危险性(RR)为0.68,95％可信区间为0.46～1.01);ASA组卒中、血管性死亡及心肌梗塞发生率(20.6％)显著低于对照组(31.1％)(P<0.005),ASA组卒中血管性死亡及心肌梗塞危险性较对照组降低33.8％(RR为0.66,95％可信区间为0.48～0.92);ASA组副作用发生率为18.9％,严重副作用为2.7％。
584 patients with mild ischemic stroke (MIS) or (TIA) were randomly divided into aspirin (ASA) group 301 cases and control group 283 cases, followed up for 12 to 60 (average 30.2) months and found: ASA group stroke (14.0%) was significantly lower than that of the control group (20.5%) (P <0.05). The risk of stroke and death in the ASA group was 32% lower than that in the control group (relative risk (RR) 0.68, 95% confidence interval (0.46 ~ 1.01). The incidence of stroke, vascular death and myocardial infarction in ASA group (20.6%) was significantly lower than that in control group (31.1%) (P <0.005). The risk of stroke and myocardial infarction in ASA group was significantly higher than that in control group Group had a decrease of 33.8% (RR 0.66, 95% confidence interval 0.48 ~ 0.92). The incidence of side effects in ASA group was 18.9% and the serious side effect was 2.7%.