枸椽酸氢钾钠治疗输尿管小结石的临床研究

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目的:探讨枸椽酸氢钾钠治疗输尿管小结石的临床价值。方法:将63例伴肾绞痛的输尿管小结石(<0.6 cm)患者分为用药组31例和对照组32例,均采用解痉、输液、利尿治疗,用药组加口服枸椽酸氢钾钠颗粒,并记录排石情况,排出结石的大小。结果:在观察期内用药组28例排出结石,有效率90.3%,对照组22例排出结石,有效率68.8%,两者存在统计学差异(P<0.05),排出结石的时间用药组(3.3±2.1)d,对照组(4.1±2.3)d,存在统计学差异(P<0.05),排出结石大小比B超测得均小,用药组有统计学差异(P<0.05),对照组无统计学意义(P>0.05),用药组未出现药物不良反应。结论:枸椽酸氢钾钠能有效缩小输尿管结石,加快结石的排出,是内科保守治疗输尿管小结石安全有效的辅助治疗药物。 Objective: To investigate the clinical value of potassium citrate citrate in the treatment of small ureteral calculi. Methods: Sixty-three patients with ureteral calculi (<0.6 cm) with renal colic were divided into treatment group (31 cases) and control group (32 cases). All patients were treated with antispasmodic, infusion and diuretic therapy. Potassium hydrogen sodium particles, and record the row of stone, the size of the discharge of stones. Results: In the observation period, 28 cases were discharged with stones, and the effective rate was 90.3%. In the control group, 22 cases discharged stones with an effective rate of 68.8%. There was a significant difference between the two groups (P <0.05) (3.3 ± 2.1) d, and control group (4.1 ± 2.3) d, there was a significant difference (P <0.05), the size of the discharged stones was smaller than the B-mode (P <0.05). There was no significant difference in the control group (P> 0.05). There was no adverse drug reaction in the treatment group. Conclusion: Potassium citrate and potassium sodium can effectively reduce the ureteral stones and accelerate the discharge of stones. It is a safe and effective adjuvant therapy for the conservative treatment of small ureteral stones.
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