铁是人体内含量最丰富的微量金属元素之一,广泛参与体内的代谢过程,具有重要的生理功能。铁缺乏和铁过量对机体都将产生不良影响,因此,机体需要具有严格的铁调控机制,既可提供足量的铁来发挥其生理功能,又可防止因过量而产生铁毒性,从而维持体内和细胞内的铁平衡。铁对许多基因的表达有着调控作用,在铁的吸收、转运、贮存和利用等各个环节上形成一个完整的调控体系,一方面调节自身的代 Iron is one of the most abundant trace metals in the human body and is widely involved in the body’s metabolic processes and has important physiological functions. Iron deficiency and excessive iron will have an adverse effect on the body, therefore, the body needs to have a strict iron regulation mechanism that can provide enough iron to exert its physiological function, but also to prevent excessive iron toxicity, thereby maintaining the body And intracellular iron balance. Iron plays a regulatory role in the expression of many genes, forming a complete regulatory system in all aspects of iron absorption, transport, storage and utilization, on the one hand to regulate its own generation