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报道一项有106例1型或2型糖尿病患者参加的为期1个月的多中心、开放自身对照研究,比较赖脯胰岛素75/25与人胰岛素70/30改善餐后2h血糖波动的疗效。由人胰岛素70/30转为赖脯胰岛素75/25治疗,餐后2h血糖水平及血糖波动均显著降低,且无任何显著性不良事件或持久性低血糖的发生。问卷显示更多患者倾向于应用赖脯胰岛素75/25。
A one-month, multicenter, open-label, self-controlled study of 106 patients with type 1 or type 2 diabetes mellitus was reported to compare the effects of insulin lispro 75/25 and human insulin 70/30 on 2-h postprandial blood glucose fluctuations. From human insulin 70/30 to insulin lispro 75/25 treatment, 2h postprandial blood glucose levels and blood glucose fluctuations were significantly reduced, and without any significant adverse events or persistent hypoglycemia. The questionnaire showed that more patients tended to apply insulin lispro 75/25.