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超声调制光学成像技术融合了光学成像和超声成像的优点,已实现对浑浊介质内隐藏异体的成像,是一种很有前景的医学成像技术。通过实验探究超声调制光信号与组织光学特性的关系、超声焦区内外组织的光学特性对调制信号的影响,发现超声对光信号的调制深度与超声焦区组织的光学性质呈简单的线性关系,调制深度随样品散射系数的增大而减小,随样品吸收系数的增大而增大。超声区信号调制深度基本不受超声调制区域外复杂组织的光学特性的影响。这为超声调制光学成像提供必要的图像重构依据。
Ultrasound-modulated optical imaging combines the advantages of optical imaging and ultrasound imaging and has enabled the imaging of hidden foreign bodies in turbid media, a promising medical imaging technique. The relationship between the optical signal and the optical characteristics of the tissue was investigated through experiments. The optical characteristics of the optical system inside and outside the focal region of the ultrasound were analyzed. The results showed that the optical depth of the optical signal was linear with the optical properties of the optical region, The modulation depth decreases with the increase of the scattering coefficient of the sample and increases with the absorption coefficient of the sample. The depth of signal modulation in the ultrasound region is basically unaffected by the optical characteristics of the complex tissue outside the ultrasound modulation region. This provides the necessary image reconstruction basis for ultrasonic modulated optical imaging.