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目的探讨荧光支气管镜(AFB)对中央型肺癌患者的临床应用价值。方法选取2011年9月至2013年8月行AFB检查并最终经支气管镜确诊的肺癌患者100例,并对其检查结果进行分析。通过普通白光(WLB)和自体荧光成像(AFI)两种光源镜检查方式进行对比。结果 112块呈恶性改变组织中,AFI漏诊3处,漏诊率为2.7%;WLB漏诊31处,漏诊率为27.7%。结论 AFB检查能提高中央型肺癌的早期诊断率,可及早发现肺癌黏膜局部浸润,准确判断气道内肿瘤的侵犯范围,并能早期发现肺癌术后复发及支气管黏膜的转移。但该方法亦可引起一定的假阳性,在临床实际操作中应注意鉴别。
Objective To investigate the clinical value of fluorescent bronchoscopy (AFB) in patients with central lung cancer. Methods From September 2011 to August 2013, 100 patients with lung cancer who were diagnosed by AFB and finally diagnosed by bronchoscopy were selected and their results were analyzed. Comparisons were made by two light source microscopy methods, normal white light (WLB) and autofluorescence imaging (AFI). Results Of the 112 malignant tissues, 3 were missed by AFI, with a misdiagnosis rate of 2.7%. WLB missed 31 lesions with a missed diagnosis rate of 27.7%. Conclusion AFB can improve the early diagnosis rate of central lung cancer, detect the local infiltration of lung mucosa as early as possible, and accurately determine the extent of invasiveness of the airway tumor. Early detection of postoperative lung cancer recurrence and bronchial mucosal metastasis can be achieved. However, this method can also cause some false positives and should pay attention to the identification in clinical practice.