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为弄清多价疫苗中增加若干血清型的潜在影响 ,作者在恒河婴猴中研究了不同剂量多糖 (PS)、载体蛋白及结合物对 6 B型肺炎球菌结合疫苗 (PCV)抗体应答结果的影响。 用 0 .0 2 5～ 2 5 μg不同剂量的 6 B型肺炎球菌 PS-脑膜炎球菌外膜蛋白复合物结合疫苗 (6 B- OMPC)于 0和 2
To understand the potential impact of increasing the number of serotypes in polyvalent vaccines, we investigated the effect of different doses of polysaccharide (PS), carrier proteins and conjugates on the response of antibodies against type 6 pneumococcal conjugate vaccine (PCV) Impact. With 0. 025 ~ 25 μg of different doses of 6-type pneumococcal PS-meningococcal outer membrane protein complex conjugate vaccine (6-OMPC) at 0 and 2