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发育制约因素下的遗传改造是“进化-发育”概念框架的中心原则。在形态改造的发育过程中,某些分子调控通路以相似的方式进行着,如与昆虫和脊椎动物眼发育密切相关的Pax6基因,对四足动物的肢体和鱼鳍发育非常重要的Hox基因,都例证了这种“深同源性”的存在。“进化-发育”理论已扩展到对行为特征进行分子生物学研究,包括语言的研究,如语言相关基因FOXP2已得到鉴定。本文综述了比较法运用于语言研究的必要性以及不同动物模型脑发育过程中FOXP2的表达研究,以期了解FOXP2是否是人类语言和动物交流系统中“深同源性”的另一案例。
Genetic modification under developmental constraints is the central principle of the “evolution-development” conceptual framework. During the development of morphological transformation, some of the molecular regulatory pathways are performed in a similar way, such as the Pax6 gene, which is closely related to eye development in insects and vertebrates, the Hox gene, which is essential for the development of limbs and fins of quadrupeds, Both exemplify the existence of this “deep homology”. Evolutionary-developmental theory has been extended to conduct molecular biology studies of behavioral traits, including language studies such as the identification of the gene FOXP2 as a language-related gene. This article reviews the necessity of comparative studies in language studies and the study of FOXP2 expression in different animal models of brain development in order to understand whether FOXP2 is another case of “deep homology” in human language and animal communication systems.