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1临床资料患者男,14岁,学生。5个月前,患者无明显原因出现面部红斑,伴脱屑和瘙痒,当地医院以“湿疹”治疗(具体不详),未见好转,症状逐渐加重;3周前,每晚突发双下肢肌肉痉挛,1~2min后即缓解,2~3次/晚;1周前,行走时感左下肢无力,不能抬腿,下蹲后不能站起,后逐渐发展为四肢对称性近端肌无力,上楼梯及穿衣困难,不能行走,进食固体食物困难及饮水呛咳,伴发热、咽痛和咳嗽咯痰,T38~38.5℃,无头晕、头痛、恶心呕吐、腹痛腹泻和关节痛等。患者既往体健,无家族遗传史。体
1 Clinical data Patient male, 14 years old, student. 5 months ago, there was no obvious cause of facial erythema in patients with scaling and itching, the local hospital to “eczema” treatment (specifically unknown), did not improve, the symptoms gradually aggravated; 3 weeks ago, Lower extremity muscle spasm, 1 ~ 2min after the relief, 2 to 3 times / night; 1 week ago, walking sense of the left lower limb weakness, can not lift the leg, can not stand after squatting, and gradually developed into limb symmetry of the proximal muscle Weakness, difficulty in climbing stairs and clothes, unable to walk, difficulty eating solid food and choking cough with fever, sore throat and cough expectoration, no dizziness, headache, nausea and vomiting, abdominal pain and diarrhea and joint pain, etc. . Past patient health, no family history. body