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目的:探讨子宫内膜异位症(EMs)与自然流产的相关性。方法:回顾性分析行IVF-ET妊娠的周期,其中EMs患者903个周期、单纯男性因素者643个周期及单纯输卵管因素者720个周期,比较分析基础FSH值、β-hCG检测阳性率(临床妊娠前)、稽留流产率和自然流产率(临床妊娠后)等指标。结果:基础FSH值EMs组高于男性因素组和输卵管因素组;平均年龄EMs组略大于输卵管因素组及男性因素组,平均不孕年限3组间无统计学差异;临床妊娠率EMs组(32.1%)与输卵管因素不孕组(33.6%)无统计学差异(P>0.05),但显著低于男性因素组(45.7%);稽留流产率、异位妊娠率妊娠率3组间无统计学差异(P>0.05);EMs组自然流产率(9.1%)高于男性因素不孕组(1.0%)和输卵管因素组(4.5%),差异显著(P<0.05)。结论:EMs患者自然流产率高于输卵管因素不孕及单纯男性因素不孕的患者。
Objective: To investigate the relationship between endometriosis (EMs) and spontaneous abortion. Methods: The pregnancy cycles of IVF-ET were retrospectively analyzed. Among them, 903 cycles of EMs, 643 simple cycles of males and 720 simple cycles of tubal factors were analyzed. The positive rates of basal FSH and β-hCG were compared Before pregnancy), missed abortion rate and spontaneous abortion rate (after clinical pregnancy) and other indicators. Results: The average value of FSH in EMs group was higher than those in male and tubal factors group. The average age of EMs group was slightly larger than those in tubal factor group and male factor group. There was no significant difference in the mean duration of infertility between the three groups. The clinical pregnancy rate in EMs group (32.1 %) And tubal infertility group (33.6%) had no statistical difference (P> 0.05), but significantly lower than the male factor group (45.7%); missed abortion rate, ectopic pregnancy rate of pregnancy rate between the three groups no statistical (P> 0.05). The spontaneous abortion rate (9.1%) in EMs group was significantly higher than that in male infertility group (1.0%) and fallopian tube factor group (4.5%) (P <0.05). Conclusions: The spontaneous abortion rate of patients with EMs is higher than that of tubal infertility and infertile men.