医院获得性感染是重症监护病房(ICU)内患者常见的疾病之一,因其感染类型多、重症感染多、治疗难度大、病死率较高而备受关注.但随着抗菌药物的使用,细菌耐药性日趋严重,使用抗菌药物已不是解决感染问题的理想方案,从根源预防和控制感染,减少感染的发生才是关键.尤其针对某些特定类型的医院获得性感染,如医院获得性肺炎(HAP)、呼吸机相关肺炎(VAP)等,还需采取综合性的预防措施,以此突破ICU感染的魔咒.“,”Nosocomial infection is one of the most common diseases in the intensive care unit (ICU), which has received much concern due to its multi-type infection, more severe infection, difficulty in treatment and high mortality. However, the drug resistance of bacteria is increasingly serious with the wide use of the antibiotics which is no longer an ideal strategy. Instead, the control and prevention of infection from their sources is the key to reduce ICU infection. Especially for some particular nosocomial infections, such as hospital acquired pneumonia (HAP) and ventilator associated pneumonia(VAP), comprehensive measures are needed to take to break the spell of ICU infection.