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目的观察阿奇霉素治疗急性肠炎治疗中的合理应用及其临床价值。方法将2014年3月-2015年3月医院确诊并收治的104例急性肠炎患者,按照就诊顺序随机分为观察组和对照组各52例。均给予对症基础性治疗,另外对照组同时给予常规静脉滴注阿奇霉素,观察组则根据患者的具体病情以及阿奇霉素的药理毒理作用给予口服或静脉滴注阿奇霉素。比较2组临床疗效、治疗费用及不良反应情况。结果观察组总有效率为96.15%显著高于对照组的80.77%,观察组不良反应发生率为9.62%显著低于对照组的21.15%,观察组平均治疗费用为(248.73±56.29)元明显低于对照组的(326.88±72.43)元,观察组应用阿奇霉素占总医疗费用为6.24%明显低于对照组的15.78%,组间差异均具有统计学意义(P<0.05)。结论阿奇霉素合理应用对治疗急性肠炎具有较好的疗效,且不良反应较少,治疗费用低,值得临床推广及广泛应用。
Objective To observe the rational use of azithromycin in the treatment of acute enteritis and its clinical value. Methods A total of 104 patients with acute enteritis diagnosed and treated in our hospital from March 2014 to March 2015 were randomly divided into observation group (52 cases) and control group (52 cases). All patients were given symptomatic basic treatment. In addition, the control group was given routine intravenous azithromycin, while the observation group was given azithromycin orally or intravenously according to the patients’ specific condition and the pharmacology and toxicology of azithromycin. The clinical efficacy, treatment costs and adverse reactions of the two groups were compared. Results The total effective rate was 96.15% in the observation group and 80.77% in the control group. The adverse reaction rate in the observation group was 9.62%, which was significantly lower than that in the control group (21.15%). The average treatment cost in the observation group was (248.73 ± 56.29) Yuan significantly lower In the control group (326.88 ± 72.43) yuan, the total cost of medical treatment of azithromycin in the observation group was 6.24%, which was significantly lower than that of the control group (15.78%). There were significant differences between the two groups (P <0.05). Conclusion The reasonable application of azithromycin in the treatment of acute enteritis has better curative effect with less adverse reactions and low cost of treatment, which is worthy of clinical promotion and extensive application.