暴发性肝功能衰竭的病因和病理类型暴发性肝功能衰竭是一种多病因的严重综合征,其基本病理变化可分为3型:(一)急性肝坏死(坏死型):最主要的病因是暴发性病毒性肝炎,甲型、乙型、非甲非乙型肝炎皆可引起。其中乙型暴发性肝炎最常见,发病机制是病毒诱发的免疫反应;甲型暴发性肝炎较少见,发病机制是肝细胞感染过量病毒。本型基本是不可逆性改变,病死率极高。 The causes and pathological types of fulminant hepatic failure fulminant hepatic failure is a multi-etiological syndrome, the basic pathological changes can be divided into 3 types: (A) of acute liver necrosis (necrosis): the most important cause Is fulminant viral hepatitis, A, B, non-A non-B can be caused. One of the most common type B fulminant hepatitis, the pathogenesis of the virus-induced immune response; fulminant hepatitis A rare, the pathogenesis of over-infection of hepatocytes. This type is basically irreversible change, high mortality.