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选取2013年1月~2014年6月在我院接受治疗的幽门螺杆菌感染并发胃溃疡患者54例为研究对象,随机分为对照组和观察组各27例,对照组患者进行标准三联疗法,观察组患者进行序贯疗法,观察两组患者的临床治疗效果及不良反应。观察组治疗有效率为96.3%,对照组治疗有效率为81.48%,两组患者治疗效果对比,差异有统计学意义(P<0.05)。对照组患者治疗过程中共7例患者出现不良反应,观察组患者治疗过程中有2例患者出现不良反应,观察组不良反应发生情况明显少于对照组,差异有统计学意义(P<0.05)。幽门螺杆菌感染是引发胃溃疡的病理机制,采取序贯疗法对HP感染并发GU效果良好,且无严重不良反应,可在临床治疗中广泛应用。
54 patients with Helicobacter pylori infection complicated with gastric ulcer who were treated in our hospital from January 2013 to June 2014 were selected as study object and randomly divided into control group and observation group with 27 cases each. Patients in control group received standard triple therapy, Patients in observation group were treated with sequential therapy, and the clinical effects and adverse reactions in both groups were observed. The observation group, the effective rate was 96.3%, the control group, the effective rate was 81.48%, two groups of patients with treatment effect, the difference was statistically significant (P <0.05). A total of 7 patients in the control group experienced adverse reactions during the course of treatment. Two patients in the observation group experienced adverse reactions during the course of treatment. The incidence of adverse reactions in the observation group was significantly less than that in the control group (P <0.05). Helicobacter pylori infection is the pathological mechanism of gastric ulcer, sequential therapy for HP infection complicated with GU effect is good, and no serious adverse reactions, can be widely used in clinical treatment.