采用 Seldinger’法对 6例局部晚期的乳腺癌进行灌注化疗 ,结果 ,6例患者肿瘤均有不同程度缩小 ,原固定的肿瘤可推动 ,并能行外科手术切除 ,经随访 2例于术后 1年余死于广泛转移 ,另 4例健在 ,生存超过 16～ 2 4个月 ,局部未见复发。认为介入化疗能使局部晚期的乳腺癌肿缩小 ,为手术切除肿瘤创造条件 ,同时可使部分原属较晚期的乳腺癌最终获得根治性治疗。 Six patients with locally advanced breast cancer were treated with infusion chemotherapy by Seldinger’s method. As a result, the tumors of 6 patients were all reduced to varying degrees. The original fixed tumor was able to be excised and surgical resection was performed. Two patients were followed up for 1 More than a year died of extensive metastasis, the other 4 cases alive, survived more than 16 ~ 24 months, no recurrence of the local. That interventional chemotherapy can make local advanced breast cancer shrink, to create the conditions for surgical resection of the tumor, while allowing some of the more advanced breast cancer eventually get radical treatment.