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目前,尚无治疗慢性丁型肝炎的有效药物。干扰素由于其广谱的抗病毒和免疫调节作用,极有可能成为治疗这一疾病的良药。为了评估干扰素治疗慢性丁型肝炎的疗效,作者进行了此项随机对照试验。 42例慢性丁型肝炎患者被随机分成三组(各14例);第一组和第二组分别给予9MU和3MU重组α-2a干扰素肌肉注射,每周3次,共48周;第三组为对照组,不接受治疗。所有参试病人年龄在18～60岁;参试前6个月内有三次血清HBsAg阳性,抗-HDVIsG和IgM阳性及HDV RNA阳性;参试
At present, there is no effective drug for the treatment of chronic hepatitis. Due to its broad spectrum of anti-viral and immunomodulatory effects, interferon is likely to become a good medicine for the treatment of this disease. To assess the efficacy of interferon in the treatment of chronic hepatitis B, the authors conducted this randomized controlled trial. Forty-two patients with chronic hepatitis D were randomly divided into three groups (14 in each). The first and second groups were intramuscularly injected with 9MU and 3MU of recombinant interferon alpha-2a for 48 weeks each week for 48 weeks. The third Group as control group, do not receive treatment. All patients aged 18 to 60 years; three months before the test serum HBsAg positive, anti-HDVIsG and IgM positive and HDV RNA positive; test