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目的 探讨孕妇自控硬膜外镇痛 (PCEA)对产程的影响。方法 3 5例使用PCEA(A组 ) ,4 0例为对照组 (B组 ) ;测定两组母血、脐血和羊水中前列腺素E2 (PGE2 )浓度 ;观察产痛程度、产程进展。结果 用药后两组产痛评分比较有显著差异 (P <0 0 5 ) ;两组内、组间母血、脐血和羊水中PGE2 、活跃期与第三产程时间及剖宫产率的比较均无显著差异 (P >0 0 5 ) ;两组第二产程时间、阴道手术助产率比较有显著差异 (P <0 0 5 )。结论 PCEA镇痛效果好 ,对母儿均无明显影响 ,值得在临床推广。
Objective To investigate the effect of controlled epidural analgesia (PCEA) on labor process in pregnant women. Methods 35 cases of PCEA (A group) and 40 cases of control group (B group); determination of prostaglandin E2 (PGE2) concentrations in maternal blood, cord blood and amniotic fluid in two groups; observed the degree of labor pain, labor progress. Results The pain scores of two groups were significantly different after treatment (P <0.05). The intra-and inter-group comparison of PGE2, active stage, third stage of labor and cesarean section in maternal blood, umbilical cord blood and amniotic fluid There was no significant difference between the two groups (P> 0.05). There was a significant difference in the second stage of labor and vaginal surgery between two groups (P <0.05). Conclusion PCEA analgesic effect is good, no significant effect on the mother and child, it is worth in the clinical promotion.