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目的探讨阿奇霉素序贯疗法对小儿支原体肺炎的治疗效果。方法将98例小儿支原体肺炎患者按照入院时间先后顺序随机分为两组,每组49例,分别标记为对照组、实验组。对照组患者给予阿奇霉素静脉连续滴注,实验组患者采用阿奇霉素静脉注射,连续5 d后转为阿奇霉素口服治疗,比较两组患者治疗效果。结果实验组患者治疗有效率为91.83%,对照组治疗有效率为59.18%,两组比较差异具有统计学意义(P<0.05)。实验组患者8例患者发生不良反应,发生率为16.32%,对照组患者24例患者发生不良反应,发生率为48.97%,两组患者比较差异具有统计学意义(P<0.05)。结论阿奇霉素序贯疗法治疗小儿支原体肺炎临床疗效确切,不良反应较少,值得临床推广应用。
Objective To investigate the effect of sequential therapy of azithromycin on mycoplasma pneumonia in children. Methods 98 cases of children with mycoplasma pneumonia were randomly divided into two groups according to the sequence of admission time, 49 cases in each group, which were marked as control group and experimental group respectively. Patients in the control group were given continuous intravenous infusion of azithromycin. Patients in the experimental group were treated with azithromycin intravenously for 5 days and then treated with azithromycin for oral treatment. The therapeutic effect was compared between the two groups. Results The effective rate was 91.83% in the experimental group and 59.18% in the control group. The difference between the two groups was statistically significant (P <0.05). Adverse reactions occurred in 8 patients in the experimental group, with an incidence rate of 16.32%. In the control group, 24 patients developed adverse reactions, with a rate of 48.97%. The difference between the two groups was statistically significant (P <0.05). Conclusion Sequential azithromycin treatment of children with mycoplasma pneumonia clinical curative effect, adverse reactions less, worthy of clinical application.