代谢综合征是一种多种代谢异常同时并存,导致对健康产生严重危害的症候群。自发性高血压大鼠具有较高的高血压发生率,其亚系大鼠已在代谢综合征的相关研究中得到了一定程度的运用。本文将对自发性高血压亚系大鼠在代谢综合征大鼠模型中应用的研究进展作一综述,为在代谢综合征研究中合理选择不同特点的自发性高血压亚系大鼠提供参考依据。 Metabolic syndrome is a syndrome in which multiple metabolic abnormalities coexist, leading to serious health risks. Spontaneous hypertensive rats have a high incidence of hypertension, and their sub-line of rats has been in the relevant studies of metabolic syndrome has been a degree of use. This article reviews the research progress of spontaneously hypertensive subline rats in the metabolic syndrome rat model and provides a reference for rational selection of spontaneously hypertensive subgroup rats with different characteristics in the study of metabolic syndrome .