惊厥是新生儿期常见的症候群,发病有两个高峰,生后3天以内和1～2周。其发生率在世界各地差别颇大,约在1.5‰～20‰。出生体重<2500克的新生儿发生率可达20%。随着围产医学的发展,死亡率已从10年前的40%下降到15%,但其神经系统的后遗症仍高达14～61%之间,严重影响小儿智力的发育。由于新生儿大脑皮层和皮层下结构在形态、生化和生物电连接方面不成熟,惊厥的病因、临床表现、脑电图特点、诊断、治疗和预 Convulsion is a common neonatal syndrome, the incidence of two peaks, less than 3 days after birth and 1 to 2 weeks. The incidence varies widely around the world, about 1.5 ‰ ~ 20 ‰. Newborns with a birth weight of <2500 grams have a 20% incidence. With the development of perinatal medicine, the mortality rate has dropped from 40% 10 years ago to 15%. However, the neurological sequelae are still as high as 14 to 61%, seriously affecting the development of children’s intelligence. Because neonatal cerebral cortex and subcortical structures are immature in terms of morphological, biochemical and bioelectrical connectivity, the etiology, clinical manifestations, features of EEG, diagnosis, treatment and pre-eclampsia