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目的 观察复方丹参治疗新生儿缺氧缺血性脑病 (HIE)的疗效 ,探讨新生儿行为神经评分 (NBNA)在评估其疗效及预后中的意义。方法 对 40例HIE在常规治疗同时给予复方丹参治疗 ,对照组 3 5例采用常规治疗 ,以NBNA进行疗效评价 ,并与Gesell发育测试法相比较。结果 两组近期疗效差异显著 ,(P <0 0 1) ,两组NBNA在第 3天无差异 (P >0 0 5 ) ,第7、14天时治疗组明显高于对照组 (7天时P <0 0 5 ,14天时P <0 0 1) ,并与Gesell发育测试结果呈正相关。结论 复方丹参治疗新生儿HIE疗效好 ,NBNA是评估复方丹参治疗新生儿HIE疗效及预后的一种有效方法。
Objective To observe the curative effect of Fufang Danshen on neonatal hypoxic-ischemic encephalopathy (HIE) and to explore the significance of neonatal behavioral neurological score (NBNA) in assessing its curative effect and prognosis. Methods Forty cases of HIE were treated with compound Salviae Miltiorrhizae simultaneously. Routine treatment was given in 35 cases in the control group, NBNA was used to evaluate the efficacy, and compared with Gesell test. Results There was significant difference in short-term curative effect between the two groups (P <0.01). There was no difference in NBNA between the two groups on the third day (P> 0.05). On the 7th and 14th day, the NBNA was significantly higher in the treatment group than in the control group (P < 0 0 5, 14 days P <0 01), and was positively correlated with the Gesell test. Conclusion Compound Salvia Miltiorrhiza treatment of neonatal HIE good effect, NBNA is to evaluate the efficacy of compound Danshen neonates HIE treatment and prognosis of an effective method.