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目的建立单笼饲养食蟹猴血液常规和血清生化的参考值,了解检测指标的性别差异。方法选取254只3~5岁健康食蟹猴,雄性84只,雌性170只,在清醒状态下采血。采用全自动血细胞分析仪和全自动生化分析仪检测血液常规和生化指标,并比较不同性别组间的差异。结果经统计分析,获取了单笼饲养食蟹猴血液常规和血清生化的参考值,雌雄食蟹猴血常规指标比较,RBC、HGB、MCHC、HCT、MONO、RDW-CV、MPV、PCT、P-LCR、PDW存在极显著性差异(P<0.01),BASO、NEUT%、LYMPH%、MCH、RDW-SD存在显著性差异(P<0.05),雌雄血生化指标比较,ALT、AST、ALP存在极显著性差异(P<0.01)。结论建立了3~5岁食蟹猴血液常规和血清生化的参考值,同时表明部分指标存在性别差异。
Objective To establish a reference standard for blood routine and serum biochemistry in caged monkeys fed with a single cage to understand the gender differences in the detection indexes. Methods A total of 254 healthy cynomolgus monkeys aged 3 to 5 years old, 84 males and 170 females, were selected for blood sampling. The blood routine and biochemical indexes were detected by automatic hematology analyzer and automatic biochemical analyzer, and the differences between different sex groups were compared. Results According to the statistical analysis, the blood routine and serum biochemical values of single caged crabs were obtained. The blood routine indexes of male and female cynomolgus monkeys were compared, including RBC, HGB, MCHC, HCT, MONO, RDW- CV, MPV, PCT, P (P <0.01). There were significant differences in BASO, NEUT%, LYMPH%, MCH and RDW-SD between the two groups (P <0.05). The levels of ALT, AST and ALP Very significant difference (P <0.01). Conclusion The blood routine and serum biochemical reference values of 3 ~ 5 years old cynomolgus monkeys were established. At the same time, some indicators showed gender differences.