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目的观察奥尔芬(双氯芬酸钠盐酸利多卡因注射液)联合硫酸镁治疗急性肾绞痛的临床疗效。方法将我院2010年6月至2011年5月接诊的458例输尿管结石所致急性肾绞痛病例随机分为两组,A组采用奥尔芬和硫酸镁联用治疗;B组采用杜冷丁和654-2联用治疗;用药后30 min进行疗效比较。结果肾绞痛缓解的总有效率:A组为97.4%,B组为97.35%,无显著差异,A组平均起效时间(15.5±4.5)min短于B组(17.4±4.9)min(P<0.01)。结论奥尔芬联合硫酸镁在急性肾绞痛治疗中有较高疗效,且副作用少,值得临床推广。
Objective To observe the clinical efficacy of olfen (diclofenac sodium and lidocaine hydrochloride injection) combined with magnesium sulfate in the treatment of acute renal colic. Methods A total of 458 cases of acute renal colic caused by ureteral calculi admitted from June 2010 to May 2011 in our hospital were randomly divided into two groups. Group A was treated with combination of Orfen and magnesium sulfate. Group B Cold Ding and 654-2 combination therapy; 30 min after treatment efficacy comparison. Results The total effective rate of renal colic relief was 97.4% in group A and 97.35% in group B, and the mean effective time in group A was shorter than that in group B (17.4 ± 4.9) min (P <0.01). Conclusion Olfen combined with magnesium sulfate in the treatment of acute renal colic have a higher efficacy, and fewer side effects, it is worth clinical promotion.