药品的溶解度是一种物理属性,是个常数,在一定程度上可以反映药物的纯度以至真伪。药典将溶解度置“性状”项下,因不作为鉴别和含量测定项目,往往在常规检验时容易被忽略不测。我们发现氯化钠在乙醇中的溶解度与1985年版中国药典的规定不符。故收集各厂家不同批次的氯化钠,严格按药典方法复测。同时按1980年版英国药典氯化钠“溶解度”项下:本品溶于250份96%乙醇或溶于10份丙三醇的规定作对照试验。 Drug solubility is a physical property, is a constant, to some extent, can reflect the purity of the drug as well as authenticity. Pharmacopoeia will set the solubility “traits ” under the item because it is not as an identification and determination of items, often easy to be neglected in the routine test. We found that the solubility of sodium chloride in ethanol does not match the requirements of the 1985 Chinese Pharmacopoeia. Therefore, different batches of sodium chloride manufacturers collected, in strict accordance with the pharmacopoeia retest. At the same time according to the 1980 edition of the British Pharmacopoeia sodium chloride “solubility ” under: This product is soluble in 250 parts of 96% ethanol or dissolved in 10 parts glycerin control test.