对９例鼻腔鼻窦胚胎性横纹肌肉瘤标本进行免疫组织化学ＬＳＡＢ法标记染色，ＨＨＦ－３５均呈阳性，ＬＣＡ，ＮＳＥ，ＣＫ，Ｓ－１００均呈阴性。提示ＨＨＦ－３５对鼻腔鼻窦胚胎性横纹肌肉瘤的诊断是敏感的指标。另用电镜对其中３例进行观察，２例见细胞胞质内有大量的糖元，１例见横纹＂Ｚ＂线结构。表明免疫组织化学和电镜检查是鼻腔鼻窦胚胎性横纹肌肉瘤有用的诊断方法。 Nine specimens of nasal sinus embryonal rhabdomyosarcoma were stained immunohistochemically with LSAB method. HHF-35 was positive, but LCA, NSE, CK and S-100 were all negative. Tip HHF-35 nasal sinus embryonal rhabdomyosarcoma diagnosis is sensitive indicators. In addition, electron microscopy was used to observe 3 of them. In 2 cases, a large amount of glycogen was found in the cytoplasm of the cells, and in 1 case, a horizontal “Z” line structure was observed. Immunohistochemistry and electron microscopy showed that nasal sinus embryonal rhabdomyosarcoma is a useful diagnostic method.