目的:总结输尿管口旁浅表性膀胱肿瘤微创治疗的临床经验。方法:在连续硬脊膜外麻醉+患侧闭孔神经阻滞麻醉下行内腔镜手术治疗输尿管口旁浅表性膀胱肿瘤患者25例,其中21例肿瘤位于输尿管口周围2.0cm以内,但未累及输尿管口;4例肿瘤基底位于输尿管口内。经尿道先置入70°膀胱镜了解肿瘤具体情况,然后更换电切镜,从基底部将肿瘤及包括输尿管口在内的周围2cm正常膀胱黏膜快速一并完整切除。结果:25例手术均顺利结束,无出血、穿孔等并发症。25例均获得随访,时间为12～24个月,无输尿管口狭窄、闭锁、严重的膀胱-输尿管反流、肾功能受损等并发症发生。结论:经尿道微创手术治疗输尿管口旁浅表性膀胱肿瘤,操作简单,创伤小,可代替开放性手术。 Objective: To summarize the clinical experience of minimally invasive treatment of superficial bladder tumors in the mouth of the ureter. Methods: Twenty-five patients with superficial urinary bladder tumor underwent transurethral esophagectomy under continuous epidural anesthesia and ipsilateral obturator nerve block anesthesia. Twenty-one of the 21 patients were located within 2.0cm around the ureteral orifice but not yet Involving the ureter mouth; 4 cases of tumor base located in the ureter mouth. Transurethral first into the 70 ° cystoscopy to understand the specific conditions of the tumor, and then replace the resectoscope, from the basal part of the tumor and including the ureteral orifice, including the surrounding 2cm normal bladder mucosa quickly and completely removed. Results: All the 25 surgeries were completed without complications of bleeding and perforation. Twenty-five patients were followed up for 12 to 24 months. No ureteral orifice stenosis, atresia, serious bladder-ureter reflux and impaired renal function were observed. Conclusion: Transurethral minimally invasive surgery in the treatment of ureteral paraepithelial superficial bladder tumor, simple operation, less trauma, can replace open surgery.