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目的观察老年冠心病患者小血管置入国产EXCEL支架的安全性与有效性。方法本研究对老年冠心病患者单纯置入小血管支架(支架直径<3.0 mm,297例)和单纯置入大血管支架(直径≥3.0 mm,405例)进行对比分析,术后6、12、18个月进行随访,观察临床不良事件(major adverse cardiac events,MACE)发生情况及血栓发生率。结果 6～18个月时两组间MACE事件、靶病变血运重建(target lesion revascularization,TLR)、心源性病死率差异无统计学意义,但非致命性急性心肌梗死(myocardial infarction,MI)及累计血栓事件老年小血管支架组较大血管组增加(P<0.05)。结论老年冠心病患者小血管内置入国产EXCEL比同龄大血管冠心病患者血栓累计发生率高。
Objective To observe the safety and efficacy of small vessel embolization of domestic EXCEL stent in elderly patients with coronary heart disease. Methods In this study, the elderly patients with coronary heart disease were treated with simple stenting (stent diameter <3.0 mm, 297 cases) and simple stenting (diameter ≥3.0 mm, 405 cases) The patients were followed up 18 months to observe the incidence of major adverse cardiac events (MACE) and the incidence of thrombosis. Results There was no significant difference in MACE, target lesion revascularization (TLR) and cardiogenic mortality between the two groups at 6-18 months. However, non-fatal myocardial infarction (MI) And thrombocytopenia in elderly patients with small vessel stent vascular group increased (P <0.05). Conclusion The cumulative incidence of thrombosis in elderly patients with coronary heart disease with small vessel internal EXCEL is higher than that of the same age coronary artery disease.