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目的:对雅丽蔓总黄酮进行体外抗真菌实验,测定其最小抑菌浓度(MIC)值。方法:采用NCCLS《产孢丝状真菌的液基稀释抗真菌药敏试验参考方案》(M-38P)方案测定30株临床常见皮肤癣菌的MIC值。结果:雅丽蔓总黄酮对真菌中不同菌种的MIC90值范围为110~429ug/ml。结论:雅丽蔓总黄酮具有显著的抗真菌作用。
OBJECTIVE: To conduct in vitro anti-fungal experiments on total flavonoids of A. elegans and determine its minimum inhibitory concentration (MIC). METHODS: The MIC values of 30 clinically common dermatophytes were determined using the NCCLS “Liquid-based dilution antifungal susceptibility test reference program” (M-38P) protocol. RESULTS: The MIC90 value of the total flavonoids in the yam vine to fungi in different strains ranged from 110 to 429 ug/ml. Conclusion: The total flavonoids of Averygium has significant antifungal effects.